To investigate the genetic basis in RASopathy patients | TACG
Genes | Free Full-Text | Simultaneous Detection of NF1, SPRED1, LZTR1, and NF2 Gene Mutations by Targeted NGS in an Italian Cohort of Suspected NF1 Patients
Cross-species analysis of LZTR1 loss-of-function mutants demonstrates dependency to RIT1 orthologs | eLife
LZTR1 Gene - GeneCards | LZTR1 Protein | LZTR1 Antibody
The Noonan Syndrome Gene Lztr1 Controls Cardiovascular Function by Regulating Vesicular Trafficking | Circulation Research
Mutations in LZTR1 drive human disease by dysregulating RAS ubiquitination – Science Mission
LZTR1-Related Hypertrophic Cardiomyopathy Without Typical Noonan Syndrome Features | Circulation: Genomic and Precision Medicine
Typical 22q11.2 deletion syndrome appears to confer a reduced risk of schwannoma | Genetics in Medicine
Frontiers | Generation of a Mouse Model to Study the Noonan Syndrome Gene Lztr1 in the Telencephalon
Delineation of dominant and recessive forms of LZTR1‐associated Noonan syndrome - Pagnamenta - 2019 - Clinical Genetics - Wiley Online Library
Germline loss-of-function mutations in LZTR1 predispose to an inherited disorder of multiple schwannomas | Nature Genetics
LZTR1 Gene - GeneCards | LZTR1 Protein | LZTR1 Antibody
LZTR1 inactivation promotes MAPK/ ERK pathway activation in glioblastoma by stabilizing oncoprotein RIT1 | bioRxiv
A Chinese family with Noonan syndrome caused by a heterozygous variant in LZTR1: a case report and literature review | BMC Endocrine Disorders | Full Text
The Noonan Syndrome Gene Lztr1 Controls Cardiovascular Function by Regulating Vesicular Trafficking | Circulation Research
LZTR1 facilitates polyubiquitination and degradation of RAS-GTPases | Cell Death & Differentiation
Expanding the mutational spectrum of LZTR1 in schwannomatosis | European Journal of Human Genetics
Schematic structure of LZTR1 mutations or variants identified to date.... | Download Scientific Diagram
Noonan Syndrome spectrum panels should include mutations in LZTR1 gene
LZTR1 is a regulator of RAS ubiquitination and signaling | Science
LZTR1 Antibodies & ELISA Kits, LZTR1 Proteins
The Noonan Syndrome Gene Lztr1 Controls Cardiovascular Function by Regulating Vesicular Trafficking | Circulation Research
![PDF] Dominant Noonan syndrome-causing LZTR1 mutations specifically affect the Kelch domain substrate-recognition surface and enhance RAS-MAPK signaling | Semantic Scholar](https://d3i71xaburhd42.cloudfront.net/c5076789ebfec6246d433c911f984be32d2b239c/11-Figure8-1.png "PDF] Dominant Noonan syndrome-causing LZTR1 mutations specifically affect the Kelch domain substrate-recognition surface and enhance RAS-MAPK signaling | Semantic Scholar")
PDF] Dominant Noonan syndrome-causing LZTR1 mutations specifically affect the Kelch domain substrate-recognition surface and enhance RAS-MAPK signaling | Semantic Scholar
